Mystic may refer to:

• Mysticism, the belief in realities beyond perceptual and/or intellectual understanding
• Christian mysticism, the philosophy and practice of a direct experience of God
• Mystic BBS, a bulletin board software with integrated telnet capabilities
• Mystic (Mustang), a uniquely colored 1996 Ford Cobra
• Mystic, Connecticut, a historic seaport and tourist center
• Mystic, Iowa

Mystic River may also mean:

• Mystic River, a short river in Massachusetts
• Mystic River (film), a 2003 American film directed by Clint Eastwood
• Mystic Pizza, a 1988 film directed by Donald Petrie